Lupus Research Paper

Lupus Research Paper-74
The CDC-funded lupus registries used similar intensive methods for case finding (hospitals, specialists’ practices, health department data) and for seeing if possible cases met standard classification criteria (i.e., medical record review). Prevalence is a measurement of all individuals affected by a disease at a particular time, usually a year.Older national prevalence estimates vary widely due to differences in case definitions, small study populations, and study methods.SLE is relatively uncommon, is difficult to diagnose, and is not a reportable disease, so it is expensive to capture all diagnosed cases reliably for epidemiologic studies.

The CDC-funded lupus registries used similar intensive methods for case finding (hospitals, specialists’ practices, health department data) and for seeing if possible cases met standard classification criteria (i.e., medical record review). Prevalence is a measurement of all individuals affected by a disease at a particular time, usually a year.Older national prevalence estimates vary widely due to differences in case definitions, small study populations, and study methods.SLE is relatively uncommon, is difficult to diagnose, and is not a reportable disease, so it is expensive to capture all diagnosed cases reliably for epidemiologic studies.

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SLE also may occur with other autoimmune conditions that require additional treatments, like Sjogren’s syndrome, antiphospholipid syndrome, thyroiditis, hemolytic anemia, and idiopathic thrombocytopenia purpura.

Incidence and prevalence are terms commonly used to describe how many people have a disease or condition.

Rheumatologists sometimes use specific criteria Most people with SLE do not have family members with the disease; however, some people with SLE do have a family history of the disease.

Men and women with an immediate family member with SLE have only a slightly higher risk for the disease.

Hydroxychloroquine and corticosteroids (e.g., prednisone) are often used to treat SLE.

The FDA approved belimumab in 2011, the first new drug for SLE in more than 50 years.

The seriousness of SLE can range from mild to life-threatening.

The disease should be treated by a doctor or a team of doctors who specialize in care of SLE patients.

Adherence to treatment regimens is often a problem, especially among young women of childbearing age (15 to 44 years).

Because SLE treatment may require the use of strong immunosuppressive medications that can have serious side effects, female patients must stop taking the medication before and during pregnancy to protect unborn children from harm.

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